反应详情

To a solution of (5-tert-butyl-2-methoxy-3-nitrophenyl)methanol (0.250 g, 1.04 mmol) in ethyl acetate (10.4 mL), 10% palladium/activated charcoal (0.025 g) was added and the resulting mixture was stirred at room temperature under hydrogen atmosphere for 14 hours. After completion of the reaction, insoluble materials were filtered through a Celite pad, and the solvent was washed with ethyl acetate. The solvent of the filtrate was evaporated under reduced pressure to obtain 0.219 g (quantitative) of the crude product containing the captioned compound.

1. customAfter completion of the reaction, insoluble materials
2. filtrationwere filtered through a Celite pad
3. washthe solvent was washed with ethyl acetate
4. customThe solvent of the filtrate was evaporated under reduced pressure