反应详情

温度

50 °C

2-Oxindole (3 g) suspended in 1,2-dichloroethane was slowly treated with 3.2 ml of acetyl chloride. The resulting suspension was stirred at 50° C. for 5 hours, cooled, and poured into water. The resulting precipitate was collected by vacuum filtration, washed copiously with water and dried under vacuum to give 2.9 g (73% yield) of 5-acetyl-2-oxindole as a brown solid.

1. temperaturecooled
2. filtrationThe resulting precipitate was collected by vacuum filtration
3. washwashed copiously with water
4. customdried under vacuum