HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(thiophen-2-yl)pyrimidine → 2-[(2-Thiophen-2-ylphenyl)carbonyl]-5-(4-thiophen-2-ylpyrimidin-2-yl)octahydro-pyrrolo[3,4-c]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(thiophen-2-yl)pyrimidine | HCID 14117941 | — |
| Reactant | (Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(2-thiophen-2-yl-phenyl)-methanone | HCID 67116155 | — |
| Product | 2-[(2-Thiophen-2-ylphenyl)carbonyl]-5-(4-thiophen-2-ylpyrimidin-2-yl)octahydro-pyrrolo[3,4-c]pyrrole | HCID 52917088 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 37 and 2-chloro-4-thiophen-2-yl-pyrimidine. MS (ESI) mass calcd. for C25H22N4OS2, 458.60; m/z found, 459.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653263B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-180551427c03412f9c35d9d0cb16b85c |
| Source note | uspto-grants-2014_02 |