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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243992Generated: October 28, 2026

2-Chloro-4-methylpyrimidine → (2,4-Dimethoxy-phenyl)-[5-(4-methyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone

https://huagongshe.com/reaction/243992

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methylpyrimidineHCID 11629607—
Reactant(2,4-Dimethoxy-phenyl)-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 66211208—
Product(2,4-Dimethoxy-phenyl)-[5-(4-methyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanoneHCID 67116445—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 38 and 2-chloro-4-methylpyrimidine. MS (ESI): mass calculated for C20H24FN4O3, 368.43; m/z found 369.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-3e2e96135838425e9642176255af34ba
Source noteuspto-grants-2014_02