HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66841501, compound → HCID 66721005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66841501 | HCID 66841501 | — |
| Reactant | HCID 66841537 | HCID 66841537 | — |
| Product | HCID 66721005 | HCID 66721005 | — |
Reaction Steps
According to the debenzylation/O-alkylation/saponification sequence described in Examples 1.7, 1.8 and 1.9, respectively, starting with 665 mg (1.35 mmol) of methyl 6-[3-[(4-methoxybenzyl)oxy]-4-chlorophenyl]-5-(2-chlorophenyl)pyridine-2-carboxylate, 181 mg of 6-{4-chloro-3-[3-(dimethylamino)propoxy]phenyl}-5-(2-chlorophenyl)pyridine-2-carboxylic acid hydrochloride are obtained in the form of a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653276B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-0cd618d66fe24a95b8ca5806d2e8df4b |
| Source note | uspto-grants-2014_02 |