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HRID244484

反应详情

EQUATION

反应方程式

HRID 244484 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)[Si](C)(C)OCc1nccs1
HCID21480592

2-({[tert-Butyl(dimethyl)silyl]oxy}methyl)-1,3-thiazole

C10H19NOSSi

结构：OCc1nc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)cs1
HCID59437290

未命名化合物

PRODUCTS

生成物

1
结构：OCc1ncc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)s1
HCID68472581

未命名化合物

收率 17%

PROCEDURE

实验过程

The title compound (73.1 mg, 17% overall yield) was prepared from 2-(tert-butyldimethylsilanyloxymethyl)thiazole (242 mg, 1.06 mmol) according to methods described for the synthesis of 2,2,2-trifluoro-1-[1-(4-fluorophenyl)-1H-indazol-5-yl]-1-(2-hydroxymethyl-thiazol-4-yl)ethanol (Example 84). MS m/z 424.48 (MH+).