Trifluoroacetic acid → HCID 58579593, compound

HRID 244508Notes

Reaction equation

HRID 244508 reaction equation
C([O:5][C:6](=[O:26])[C:7]1[CH:12]=[CH:11][C:10]([N:13]2[S:17](=[O:19])(=[O:18])[C:16]3[CH:20]=[CH:21][CH:22]=[CH:23][C:15]=3[S:14]2(=[O:25])=[O:24])=[CH:9][CH:8]=1)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[O:18]=[S:17]1(=[O:19])[C:16]2[CH:20]=[CH:21][CH:22]=[CH:23][C:15]=2[S:14](=[O:25])(=[O:24])[N:13]1[C:10]1[CH:11]=[CH:12][C:7]([C:6]([OH:26])=[O:5])=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 58579585HCID 58579585, compound

Product 1

HCID 58579593HCID 58579593, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of tert-butyl-4-(1,1,3,3-tetraoxidobenzo[d][1,3,2]dithiazol-2-yl)benzoate, 5, (0.77 g; 1.8 mmol) in dichloromethane (10 mL) was treated with trifluoroacetic acid (5 mL) and allowed to stir at ambient temperature for a period of 2 hours. The solvent was removed under reduced pressure to afford 4-(1,1,3,3-tetraoxidobenzo[d][1,3,2]dithiazol-2-yl)benzoic acid, 6, (0.67 g; 84%). The compound was used without further purification.

Workup

  1. customThe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-ccf9fe5fd20e4b87911cf255d325ecaf
Source dataset
uspto-grants-2014_02
Patent number
US08658650B2

Reaction notes

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