6-(1H-Indol-4-yl)-4-nitro-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole → 6-(1H-Indol-4-yl)-2-(tetrahydro-2H-pyran-2-yl)-2H-indazol-4-amine

Participants

Reaction Steps

6-(1H-Indol-4-yl)-4-nitro-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole (2.54 g), ethyl acetate (100 ml) and 10% palladium on carbon (250 mg) were placed under an atmosphere of hydrogen and the mixture stirred overnight. The mixture was filtered through Celite and the solvent removed in vacuo to give the title compound as an off white solid (2.27 g).

Provenance & Evidence