Hydrochloric Acid → HCID 58356364, compound

Participants

Reaction Steps

1,1-Dimethylethyl 1-(1-methylethyl)-5-(4-morpholinylmethyl)-1H-pyrazole-3-carboxylate (101 mg) was dissolved in 1,4-Dioxane (2 ml). 4M hydrogen chloride in 1,4 dioxane (3 ml) was added and the mixture was stirred at RT under nitrogen for 6 h. The solvent was removed in vacuo, toluene (10 ml) was added and removed in vacuo to give a white solid. The solid was dried in a vacuum oven over-night to give the title compound (81 mg) as a white solid.

Provenance & Evidence