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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24468Generated: October 29, 2026

6-(4-Fluorophenyl)-1,3-dihydro-2H-indol-2-one → 3-{2-[6-(4-Fluorophenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-5-methyl-1H-pyrrol-3-yl}propionic Acid

https://huagongshe.com/reaction/24468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Fluorophenyl)-1,3-dihydro-2H-indol-2-oneHCID 22042172—
Reactant3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acidHCID 22135394—
Product3-{2-[6-(4-Fluorophenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-5-methyl-1H-pyrrol-3-yl}propionic AcidHCID 69763872—

Reaction Steps

6-(4-Fluorophenyl)-1,3-dihydroindol-2-one (70 mg, 0.31 mmol) was condensed with 3-(2-formyl-5-methyl-1H-pyrrol-3-yl)-propionic acid (56 mg) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-88c17c7d48db4061bbb4c4a807fa1b7c
Source noteuspto-grants-2005_02