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HRID24469

反应详情

EQUATION

反应方程式

HRID 24469 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)c1c(CCC(=O)O)c[nH]c1C
HCID21728744

2-Methyl-3-carbethoxy-4-(3-propionic acid)pyrrole

C11H15NO4

结构：O=C1Cc2ccc(-c3ccc(F)cc3)cc2N1
HCID22042172

6-(4-Fluorophenyl)-1,3-dihydro-2H-indol-2-one

C14H10FNO

结构：CCOC(=O)c1c(C)[nH]c(C=O)c1CCC(=O)O
HCID54569391

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cc(-c4ccc(F)cc4)ccc32)c1CCC(=O)O
HCID69764087

未命名化合物

PROCEDURE

实验过程

6-(4-Fluorophenyl)-1,3-dihydroindol-2-one (60 mg, 0.26 mmol) was condensed with 4-(2-carboxyethyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester (65 mg), prepared by formylation of 4-(2-carboxyethyl)-3-ethoxycarbonyl-2-methylpyrrole (Bulter, A. R., and George, S. D. (1993) Tetrahedron 49: 7017-7026), to give the title compound.