反应详情

温度

80 °C

Thionyl chloride (5 ml) was added to 4-chloro-1-ethyl-1H-pyrazole-5-carboxylic acid (1 g) and the reaction was heated at 80° C. for 6 h then cooled to room temperature overnight. The reaction was evaporated, then azeotroped with toluene to give title compound, 970 mg.

1. temperaturethen cooled to room temperature overnight
2. customThe reaction was evaporated
3. customazeotroped with toluene