HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 244690Generated: October 29, 2026
Thionyl Chloride → 4-chloro-1-ethyl-1H-pyrazole-5-carbonyl chloride
https://huagongshe.com/reaction/244690
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Chloro-1-ethyl-1H-pyrazole-5-carboxylic acid | HCID 589707 | — |
| Product | 4-chloro-1-ethyl-1H-pyrazole-5-carbonyl chloride | HCID 25220813 | — |
Reaction Steps
Thionyl chloride (5 ml) was added to 4-chloro-1-ethyl-1H-pyrazole-5-carboxylic acid (1 g) and the reaction was heated at 80° C. for 6 h then cooled to room temperature overnight. The reaction was evaporated, then azeotroped with toluene to give title compound, 970 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08658635B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-44b1240e5c0d454e8a943591fa768571 |
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| Source note | uspto-grants-2014_02 |
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