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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24471Generated: October 30, 2026

5-Chlorooxindole → 3-[2-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-5-methyl-1H-pyrrol-3-yl]propionic Acid

https://huagongshe.com/reaction/24471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-ChlorooxindoleHCID 152801—
Reactant3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acidHCID 22135394—
Product3-[2-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-5-methyl-1H-pyrrol-3-yl]propionic AcidHCID 54128247—

Reaction Steps

5-Chloro-1,3-dihydroindol-2-one (61 mg, 0.36 mmol) was condensed with 3-(2-formyl-5-methyl-1H-pyrrol-3-yl)-propionic acid (66 mg) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-496d5c51b6764accbaf764f51d64f2e1
Source noteuspto-grants-2005_02