HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(3,3-Dimethyl-but-1-ynyl)-3-(4-[1,2,4]triazol-1-yl-cyclohexylamino)-thiophene-2-carboxylic acid methyl ester → HCID 178499329, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(3,3-Dimethyl-but-1-ynyl)-3-(4-[1,2,4]triazol-1-yl-cyclohexylamino)-thiophene-2-carboxylic acid methyl ester | HCID 24988981 | — |
| Reactant | HCID 178461265 | HCID 178461265 | — |
| Product | HCID 178499329 | HCID 178499329 | — |
Reaction Steps
5-(3,3-Dimethyl-but-1-ynyl)-3-(4-[1,2,4]triazol-1-yl-cyclohexylamino)-thiophene-2-carboxylic acid methyl ester (0.27 g, 0.70 mmol) is acylated with trans-4-methylcyclohexyl carboxylic acid chloride as previously described to give 5-(3,3-dimethyl-but-1-ynyl)-3-[(trans-4-methyl-cyclohexanecarbonyl)-(4-[1,2,4]triazol-1-yl-cyclohexyl)-amino]-thiophene-2-carboxylic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08658674B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-ac521014aa7c41a388662f6457f9924f |
| Source note | uspto-grants-2014_02 |