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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245372Generated: October 29, 2026

2,6-Dimethylmorpholine, cis- → 3-chloro-2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-fluorobenzoic acid

https://huagongshe.com/reaction/245372

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylmorpholine, cis-HCID 641500—
Reactant3-Chloro-2,4-difluorobenzoic acidHCID 2773532—
Product3-chloro-2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-fluorobenzoic acidHCID 67358936—

Reaction Steps

Starting materials: 3-chloro-2,4-difluorobenzoic acid and cis-2,6-dimethylmorpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658641B2
Source datasetuspto-grants-2014_02
ORD IDord-67e4c68322944f83a0475ec2f72729a3
Source noteuspto-grants-2014_02