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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245488Generated: October 29, 2026

4,4-Difluoropiperidine → HCID 67358088, compound

https://huagongshe.com/reaction/245488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4-DifluoropiperidineHCID 2758352—
Reactantethyl 5-((tert-butyldiphenylsilyloxy)methyl)-6-((2R,6S)-2,6-dimethylmorpholino)-7-fluorobenzo[d]isoxazole-3-carboxylateHCID 67357675—
ProductHCID 67358088HCID 67358088—

Reaction Steps

Starting materials: ethyl 5-((tert-butyldiphenylsilyloxy)methyl)-6-((2R,6S)-2,6-dimethylmorpholino)-7-fluorobenzo[d]isoxazole-3-carboxylate (Intermediate 204) and 4,4-difluoropiperidine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658641B2
Source datasetuspto-grants-2014_02
ORD IDord-619d5cce598442a89f3a75da43e669c4
Source noteuspto-grants-2014_02