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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245535Generated: October 27, 2026

rel-(3R,5S)-3,5-Dimethylpiperidine → 6-((3S,5R)-3,5-dimethylpiperidin-1-yl)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde

https://huagongshe.com/reaction/245535

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrel-(3R,5S)-3,5-DimethylpiperidineHCID 641101—
ReactantHCID 86658113HCID 86658113—
Product6-((3S,5R)-3,5-dimethylpiperidin-1-yl)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehydeHCID 86658126—

Reaction Steps

Starting materials: 6,7-difluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde (Intermediate 374) and (3S,5R)-3,5-dimethylpiperidine (HCl Salt).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658641B2
Source datasetuspto-grants-2014_02
ORD IDord-1aaee412b0e64996a9cefa25369b2011
Source noteuspto-grants-2014_02