HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → N-((3-chloropyrazin-2-yl)methyl)-4-morpholinocyclohexanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | N-((3-chloropyrazin-2-yl)methyl)-4-oxocyclohexanecarboxamide | HCID 86674630 | — |
| Product | N-((3-chloropyrazin-2-yl)methyl)-4-morpholinocyclohexanecarboxamide | HCID 86674644 | — |
Reaction Steps
According to the procedure described in example 7 step 7a N-((3-chloropyrazin-2-yl)methyl)-4-oxocyclohexanecarboxamide (1 g) and morpholine (0.44 mL) gave after work-up N-((3-chloropyrazin-2-yl)methyl)-4-morpholinocyclohexanecarboxamide (1.28 g). This crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08658794B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-a99c7b8e5467417da344e96eac4442dc |
| Source note | uspto-grants-2014_02 |