Thionyl Chloride → 1,2,2-Trichlorocyclopropane-1-carbonyl chloride

HRID 246796Notes

Reaction equation

HRID 246796 reaction equation
S(Cl)([Cl:3])=O.[Cl:5][C:6]1([C:11]([OH:13])=O)[CH2:8][C:7]1([Cl:10])[Cl:9]>C1C=CC=CC=1>[Cl:5][C:6]1([C:11]([Cl:3])=[O:13])[CH2:8][C:7]1([Cl:10])[Cl:9]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14299770HCID 14299770, compound

Product 1

HCID 142997721,2,2-Trichlorocyclopropane-1-carbonyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Thionyl chloride (50 ml) was added to a solution of 1,2,2-trichlorocyclopropane carboxylic acid (47.4 grams) in 300 ml of benzene. The reaction mixture was heated to reflux temperature and stirred for approximately 20 hours. The solvents were evaporated in vacuo to provide the intermediate acid chloride derivative, 1,2,2-trichlorocyclopropane carboxylic acid chloride (43.8 grams).

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureto reflux temperature
  3. customThe solvents were evaporated in vacuo

Sources & evidence

ORD record
ord-f1e80488b731468fb8f34a1371877a1d
Source dataset
uspto-grants-1987_11
Patent number
US04704156

Reaction notes

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