反应详情

A mixture of 3,5-dimethyl-4-nitrophenol (17.6 g), benzyl chloride (20.0 g) and anhydrous K2CO3 (13.2 g) in acetone (100 ml) is stirred under reflux for 22 hours. The reaction mixture is filtered and the precipitate washed with acetone. The acetone extract is concentrated in vacuo and the residue short path distilled (160°-170° C.; 50μ) to give 22.9 grams of an orange liquid which crystallized on standing.

1. temperatureunder reflux for 22 hours
2. filtrationThe reaction mixture is filtered
3. washthe precipitate washed with acetone
4. extractionThe acetone extract
5. concentrationis concentrated in vacuo
6. distillationthe residue short path distilled (160°-170° C.; 50μ)