4-Chlorobutyronitrile → HCID 15589481, compound

HRID 247048Notes

Reaction equation

HRID 247048 reaction equation
[CH3:1][CH:2]1[CH2:7][CH:6]([CH3:8])[CH2:5][NH:4][CH2:3]1.Cl[CH2:10][CH2:11][CH2:12][C:13]#[N:14]>C1C=CC=CC=1>[CH3:1][CH:2]1[CH2:7][CH:6]([CH3:8])[CH2:5][N:4]([CH2:10][CH2:11][CH2:12][C:13]#[N:14])[CH2:3]1

Participants

4

Reactant 2

HCID 123364-ChlorobutyronitrileHCID 1182593,5-Dimethylpiperidine

Product 1

HCID 15589481HCID 15589481, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Into a solution under reflux of 50 g (0.424 mole) of 3,5 dimethylpiperidine at 96% in 60 ml benzene are run in25 minutes 22 g (0.212 mole) of 4-chlorobutyronitrile and the reflux is continued for 2h.

Workup

  1. waitare run in25 minutes

Sources & evidence

ORD record
ord-a6a24a38902a493384f6355e7d0a9614
Source dataset
uspto-grants-1987_11
Patent number
US04705795

Reaction notes

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