1,1-Dimethoxyethyl(dimethyl)amine → HCID 88646181, compound

HRID 247149Notes

Reaction equation

HRID 247149 reaction equation
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][N:6]=[CH:7][N:8]([CH3:10])[CH3:9])[CH3:2].CO[C:14](OC)([N:16]([CH3:18])[CH3:17])[CH3:15].CC([O-])(C)C.[K+]>>[CH2:1]([O:3][C:4](=[O:11])/[C:5](/[N:6]=[CH:7][N:8]([CH3:10])[CH3:9])=[C:14](\[N:16]([CH3:18])[CH3:17])/[CH3:15])[CH3:2]

Participants

4

Reactant 3

HCID 878351,1-Dimethoxyethyl(dimethyl)amineHCID 11805035HCID 11805035, compoundHCID 23665647Potassium tert-butoxide

Product 1

HCID 88646181HCID 88646181, compound

Procedure

A mixture of 4.7 g of N-(dimethylaminomethylene)-glycine-ethyl ester (W. Kantlehner et al., Liebigs Ann Chem. 1980, 344), 8 g of dimethylacetamide-dimethylacetal and 0.4 g of potassium tert-butylate, analogously to 1b), is heated for 8 hours with distilling off of the resulting alcohols. The residue is then fractionated.

Workup

  1. distillationwith distilling off of the resulting alcohols

Sources & evidence

ORD record
ord-e1462ff51c8c47d98e84af1664ceb066
Source dataset
uspto-grants-1987_11
Patent number
US04705857

Reaction notes

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