CAS 18871-66-4 1,1-Dimethoxyethyl(dimethyl)amine (HCID 87835)

Names & identifiers

Preferred name: 1,1-Dimethoxyethyl(dimethyl)amine
IUPAC: 1,1-dimethoxy-N,N-dimethylethanamine
English name: 1,1-Dimethoxy-N,N-dimethylethylamine
Molecular formula: C6H15NO2
Molecular weight: 133.19

Names & synonyms

18871-66-4Ethanamine, 1,1-dimethoxy-N,N-dimethyl-1,1-Dimethoxyethyl(dimethyl)aminedimethylacetamide dimethyl acetalEINECS 242-641-0DTXSID10172242RefChem:409937DTXCID5094733242-641-0N,N-Dimethylacetamide dimethyl acetal1,1-dimethoxy-n,n-dimethylethanamine1,1-Dimethoxy-N,N-dimethylethylamine

Show more names

N,N' DIMETHYLACacetamide dimethyL1,1-Dimethoxy-N,N-diEmpagliflozin Impurity 196DimethylacetamideDimethylacetal1,1-Dimethoxy-N,N-dimethylamine

(1,1-dimethoxyethyl)dimethylamineMFCD000084761,1-dimethoxy-N,N-dimethylethan-1-amineN,N-Dimethylacetamide dimethylacetalN,N-Dimethylacetamide dimethyl acetal, stabilized with 5-10% Methanol(1,1-Dimethoxy-ethyl)-dimethyl-amineDimethylacetamide DimethylacetalN-(1,1-Dimethoxyethyl)dimethylamine

Database identifiers

CAS: 18871-66-4
PubChem CID: 87835
DTXSID: DTXSID10172242
UNII: H3SW669ZSK
EC Number: 242-641-0
Nikkaji: J208.388D

Properties

Computed structural properties

XLogP: 0.4
Topological polar surface area: 21.7 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 3
Rotatable bonds: 3
Heavy atoms: 9
Formal charge: 0
Complexity: 79.1

Physicochemical properties

Boiling point: 118 °C · 118 °C(lit.)
Density: 0.911 g/mL · 0.911 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.411(lit.)
Flash point: 47 °F · 47 °F
storage temp.: 2 · 2-8°C
form: Liquid
pka: 5.08 · 5.08±0.50(Predicted)
color: Clear colorless
Water Solubility: Hydrolyzes in water.
Sensitive: Moisture Sensitive
BRN: 1420865 · 1420865
InChI: InChI=1S/C6H15NO2/c1-6(8-4,9-5)7(2)3/h1-5H3
InChIKey: FBZVZUSVGKOWHG-UHFFFAOYSA-N
SMILES: C(N(C)C)(OC)(OC)C
CAS DataBase Reference: 18871 · 18871-66-4(CAS DataBase Reference)
NIST Chemistry Reference: N,N-Dimethylacetamide dimethyl acetal(18871-66-4)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS06,GHS08
Signal word: Danger
Hazard statements: 225 · H225-H302-H311+H331-H315-H319-H335-H371
Precautionary statements: 210 · P210-P280-P301+P312+P330-P302+P352+P312-P304+P340+P311-P308+P311
target organs: Eyes,Central nervous system, Respiratory system
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: F,Xn
Risk Statements: 11 · 11-20/21/22-36/37/38-68/20/21/22-68
Safety Statements: 26 · 26-36/37-36/37/39-16
RIDADR: 1993 · UN 1993 3/PG 2
WGK Germany: 3 · 3
F: 8 · 8-10-21
HazardClass: 3 · 3
PackingGroup: II
HS Code: 29241990 · 29241990
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 3 DermalAcute · Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 2STOT SE 3
Limited Quantities: 1 L · 1.0 L (0.3 gallon) (liquid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H225 (92%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 50 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

Chemical: Ethanamine, 1,1-dimethoxy-N,N-dimethyl-

1,1-Dimethoxyethyl(dimethyl)amine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 2 (92%)

Safety data

F: 8-10-21
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: UN 1993 3/PG 2
hs_code: 29241990
risk_code: 11-20/21/22-36/37/38-68/20/21/22-68
Signal word: Danger
Symbol(GHS): GHS02,GHS06,GHS08
hazard_code: F,Xn
safety_code: 26-36/37-36/37/39-16
hazard_class: 3
Storage Class: 3 - Flammable liquids
packing_group: II
target organs: Eyes,Central nervous system, Respiratory system
Hazard statements: H225-H302-H311+H331-H315-H319-H335-H371
Limited Quantities: 1.0 L (0.3 gallon) (liquid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Hazard Classifications: Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 2STOT SE 3
Precautionary statements: P210-P280-P301+P312+P330-P302+P352+P312-P304+P340+P311-P308+P311

Chemistry & industry

Applications

UsesN,N-Dimethylacetamide dimethyl acetal has been used as:one carbon inserting synthon in preparation of pyrimido[1,2-a][1,3,5]triazin-6-onesreagent for the synthesis of amides, diacylamines and heterocycles

General DescriptionClaisen type reaction of N,N-dimethylacetamide dimethyl acetal using optically active trans-3-penten-2-ol as substrate has been investigated.