反应详情

To a solution of 910 mg (2.1mmole) of the title product of Example 2 in 15 ml of ethanol was added 160 mg (4 mmole) of sodium hydroxide dissolved in 15 ml of water. The mixture was stirred overnight and then acidified (ca. pH 2) with dilute hydrochloric acid. The resulting precipitate was collected by filtration, washed thoroughly with water, and dried under reduced pressure to give 680 mg of analytically pure title compound.

1. filtrationThe resulting precipitate was collected by filtration
2. washwashed thoroughly with water
3. customdried under reduced pressure