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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24730Generated: October 26, 2026

3-Methoxyaniline → (3Z)-3-[(3-methoxyanilino)-phenylmethylidene]-1H-indol-2-one

https://huagongshe.com/reaction/24730

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
ReactantSodium HydroxideHCID 14798—
Reactant1-Acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinoneHCID 69743657—
SolventTetrahydrofuranHCID 8028—
Product(3Z)-3-[(3-methoxyanilino)-phenylmethylidene]-1H-indol-2-oneHCID 178491075—

Reaction Steps

Prepared analogously to Example 2 from 1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone and 3-methoxyaniline in THF and subsequent treatment with sodium hydroxide solution.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-318a4454c4ab4a2498939cde2b72a4cc
Source noteuspto-grants-2005_02