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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24732Generated: October 26, 2026

Sodium Hydroxide → HCID 178494500, compound

https://huagongshe.com/reaction/24732

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant3-Methoxymethyl-aniline-hydrochlorideHCID 22569551—
Reactant1-Acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinoneHCID 69743657—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178494500HCID 178494500—

Reaction Steps

Prepared analogously to Example 2 from 1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone and 3-methoxymethyl-aniline-hydrochloride in THF and subsequent treatment with sodium hydroxide solution in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-48b6d2d452b74375a4e06cb6cdb23a9b
Source noteuspto-grants-2005_02