Hydrazine → HCID 178442036, compound

Participants

Reaction Steps

A mixture of 3.2 g of 1-n-pentyl-4-(trans-4-propionylcyclohexyl)-bicyclo[2.2.2]octane [obtainable by reacting 1-n-pentyl-4-(trans-4-cyanocyclohexyl)-bicyclo[2.2.2]octane (German Offenlegungsschrift Pat. No. 3,246,440) with C2H5MgBr and hydrolysing the product], 3 g of KOH, 5 ml of 85% hydrazine and 50 ml of triethylene glycol is heated at 120° C. for 1 hour. The temperature is increased slowly until the resulting hydrazone is decomposed, and the mixture is boiled for a further 4 hours, cooled and worked up in the customary manner to give 1-n-pentyl-4-(trans-4-n-propylcyclohexyl)-bicyclo[2.2.2]octane.

Provenance & Evidence