HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 178458489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Fluoropropiophenone | HCID 68004 | — |
| Reactant | 4-(1H-imidazol-4-yl)piperidine | HCID 178420873 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178458489 | HCID 178458489 | — |
Reaction Steps
3 g (0.019 mole) of 4-(4-piperidyl)-1H-imidazole and 2.88 g (0.019 mole) of para-fluoropropiophenone are stirred in 70 cm3 of dimethylformamide for 5 minutes. 4 g (0.037 mole) of disodium carbonate and 0.2 g (0.0012 mole) of potassium iodide are added and the solution is brought to 160° C. for 3 hours. After being cooled, the solution is poured into 200 cm3 of water and stirred for 1 hour. The precipitate formed is drained, washed with water, dried and recrystallized in acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707487 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-f87d3afad9354b5ab91c144186471252 |
| Source note | uspto-grants-1987_11 |