HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 247402Generated: October 27, 2026
4-Fluorobenzyl chloride → HCID 178505777, compound
https://huagongshe.com/reaction/247402
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(1H-imidazol-4-yl)piperidine | HCID 178420873 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178505777 | HCID 178505777 | — |
Reaction Steps
To a solution of 1.5 g of 4-(4-imidazolyl)piperidine in 75 cm3 of dimethyl formamide, 2 g of potassium carbonate and 1.5 g of p-fluorobenzyl chloride are added. The mixture is then heated to 80° C. with stirring for 2 hours. The mixture is filtered and the filtrate evaporated under reduced pressure. The residue is recrystallized in acetonitrile. White crystals, M.p. 232° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04707487 |
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| Source dataset | uspto-grants-1987_11 |
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| ORD ID | ord-2982e3d670d94f2d96825823237791d6 |
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| Source note | uspto-grants-1987_11 |
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