反应详情

A solution of 3,5-dichlorobenzaldehyde (0.0571 mol) and methoxyamine hydrochloride (0.0629 mol) in ethanol (50 ml) and pyridine (50 ml) was stirred 18 hours at room temperature. The reaction was concentrated and partitioned between methylene chloride and water. The organic phase was washed with 3N aqueous hydrogen chloride, dried over sodium sulfate and was concentrated to yield 10.9 g (94%) white solid, mp 53°.

1. concentrationThe reaction was concentrated
2. custompartitioned between methylene chloride and water
3. washThe organic phase was washed with 3N aqueous hydrogen chloride
4. dry with materialdried over sodium sulfate
5. concentrationwas concentrated