HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3,5-Difluorophenyl)propyl azide → 3-(3,5-Difluorophenyl)propan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3,5-Difluorophenyl)propyl azide | HCID 14049912 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(3,5-Difluorophenyl)propan-1-amine | HCID 14049913 | 96.2% |
Reaction Steps
3-(3,5-Difluorophenyl)propylazide (0.034 mol) in methanol (75 ml) was shaken with a slurry of methanol washed Raney nickel under 50 psi hydrogen for 2 hours. The reaction mixture was filtered and the filtrate concentrated to yield 5.6 g (96%) of an oily product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04707488 |
| Source dataset | uspto-grants-1987_11 |
| ORD ID | ord-b73a0a6bafe14f6ab1fa8ea9c460fcb3 |
| Source note | uspto-grants-1987_11 |