Hydrogen Bromide → HCID 20160728, compound

Participants

Reaction Steps

The sulfamoyl compound (3.7 g, 0.01 m) is suspended in 3N hydrochloric acid, heated to reflux for 16 hours and concentrated in vacuo to give 8-methoxy-1-phenyl-7-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride. 8-Methoxy-1-phenyl-7-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (3.7 g, 0.01 m) is dissolved in 48% hydrobromic acid (20 ml), refluxed for 2 hours and concentrated in vacuo to afford 8-hydroxy-1-phenyl-7-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide.

Provenance & Evidence