Hydrogen Bromide → HCID 20160686, compound

HRID 247447Notes

Reaction equation

Cl.C[O:3][C:4]1[C:20]([S:21](=[O:24])(=[O:23])[NH2:22])=[CH:19][C:7]2[CH:8]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:9][NH:10][CH2:11][CH2:12][C:6]=2[CH:5]=1.[BrH:25]>>[BrH:25].[OH:3][C:4]1[C:20]([S:21](=[O:23])(=[O:24])[NH2:22])=[CH:19][C:7]2[CH:8]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:9][NH:10][CH2:11][CH2:12][C:6]=2[CH:5]=1

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 20160708HCID 20160708, compound

Product 1

HCID 20160686HCID 20160686, compound

Procedure

7-Methoxy-1-phenyl-8-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride is treated with hydrobromic acid by the procedure of Example 2 to give 7-hydroxy-1-phenyl-8-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide.

Sources & evidence

ORD record: ord-335897c5ad4c4ead8748445cdc914469
Source dataset: uspto-grants-1987_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04707483

Reaction notes

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