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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 247451Generated: October 29, 2026

Sodium Hydroxide → HCID 20160739, compound

https://huagongshe.com/reaction/247451

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 20160710HCID 20160710—
SolventMethanolHCID 887—
ProductHCID 20160739HCID 20160739—

Reaction Steps

8-Methoxy-1-phenyl-3-trifluoroacetyl-7-trifluoromethylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine (5 g, 0.01 m) dissolved in methanol is treated with 40% aqueous sodium hydroxide and stirred. The mixture is concentrated in vacuo and partitioned between ethyl acetate and water to give 8-methoxy-1-phenyl-7-trifluoromethylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04707483
Source datasetuspto-grants-1987_11
ORD IDord-91874b6c87344f10be9b496559a0d90a
Source noteuspto-grants-1987_11