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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24752Generated: October 28, 2026

Dimethylamine, hydrochloride → HCID 178484439, compound

https://huagongshe.com/reaction/24752

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamine, hydrochlorideHCID 10473—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant3-[[(Z)-(2-oxo-1H-indol-3-ylidene)-phenylmethyl]amino]benzoic acidHCID 178517081—
SolventDimethylformamideHCID 6228—
SolventTriethylamineHCID 8471—
ProductHCID 178484439HCID 178484439—

Reaction Steps

Prepared analogously to Example 21 from (Z)-3-[1-(3-carboxyphenylamino)-1-phenyl-methylidene]-2-indolinone, dimethylamine-hydrochloride, TBTU, HOBt and triethylamine in DMF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-7543ce654e57491ba55a3a7794adc116
Source noteuspto-grants-2005_02