HCID 178450967, compound → HCID 178450964, compound

HRID 247542Notes

Reaction equation

HRID 247542 reaction equation
[CH2:1]([O:5][CH:6]([O:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:7]([CH2:23][CH2:24][CH2:25][NH:26][C:27](=[NH:29])[NH2:28])[NH:8][C:9](=[O:22])[CH2:10][NH:11]C(OCC1C=CC=CC=1)=O)[CH2:2][CH2:3][CH3:4]>CO.[Pd]>[CH2:31]([O:30][CH:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[CH:7]([CH2:23][CH2:24][CH2:25][NH:26][C:27](=[NH:28])[NH2:29])[NH:8][C:9](=[O:22])[CH2:10][NH2:11])[CH2:32][CH2:33][CH3:34]

Participants

4

Reactant 1

HCID 178450967HCID 178450967, compound

Product 1

HCID 178450964HCID 178450964, compoundYield 84.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

644 mg of the obtained N-benzyloxycarbonyl-glycyl-D,L-argininal dibutyl acetal was dissolved in 30 ml of methanol and subjected to catalytic reduction with palladium black for four hours. After the completion of the reaction, the palladium black was removed and the solvent was distilled off in vacuo to give 390 mg of glycyl-D,L-argininal dibutyl acetal in the form of a powder.

Workup

  1. customAfter the completion of the reaction
  2. customthe palladium black was removed
  3. distillationthe solvent was distilled off in vacuo

Sources & evidence

ORD record
ord-95008bdc196f43f2ba607d2b3e869606
Source dataset
uspto-grants-1987_11
Patent number
US04708944

Reaction notes

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