HRID247613

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24758

Sodium hydride

HNa

HCID31405

2,6-Di-tert-butylphenol

C14H22O

HCID87118

1-Octadecyl-1H-pyrrole-2,5-dione

C22H39NO2

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCN1C(=O)CC(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O

HCID14148376

未命名化合物

收率 37%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6386

tert-Butyl alcohol

C4H10O

PROCEDURE

实验过程

This compound is prepared by the procedure of Example 1 from 2.40 g (0.1 mol) of sodium hydride, 20.63 g (0.1 mol) of 2,6-di-tert-butylphenol, and 34.96 g (0.1 mole) of N-n-octadecylmaleimide in tert-butyl alcohol. The residue is purified by dry-column chromatography (3:1 heptane:ethyl acetate eluent) followed by recrystallization from petroleum ether to give 20.5 g (37%) of a white solid: mp 70°-73° C.

WORKUP

后处理

customThe residue is purified by dry-column chromatography (3:1 heptane:ethyl acetate eluent)
customfollowed by recrystallization from petroleum ether

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bc9998d89c954ab68c5338046a6d93d4
来源数据集: uspto-grants-1987_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04709050
来源说明: uspto-grants-1987_11

反应 SMILES

[H-].[Na+].[C:3]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:8]=1[OH:17])([CH3:6])([CH3:5])[CH3:4].[CH2:18]([N:36]1[C:40](=[O:41])[CH:39]=[CH:38][C:37]1=[O:42])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>C(O)(C)(C)C>[C:13]([C:9]1[CH:10]=[C:11]([CH:39]2[CH2:38][C:37](=[O:42])[N:36]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[C:40]2=[O:41])[CH:12]=[C:7]([C:3]([CH3:6])([CH3:5])[CH3:4])[C:8]=1[OH:17])([CH3:16])([CH3:15])[CH3:14]