Sodium ethoxide → Fenpiclonil

HRID 247627Notes

Reaction equation

HRID 247627 reaction equation
[Cl:1][C:2]1[C:15]([Cl:16])=[CH:14][CH:13]=[CH:12][C:3]=1[C:4](=O)[CH2:5][NH:6][CH:7]=[CH:8][C:9]#[N:10].CC[O-].[Na+]>C(O)C>[Cl:1][C:2]1[C:15]([Cl:16])=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]1[C:8]([C:9]#[N:10])=[CH:7][NH:6][CH:5]=1

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 679440943-(2,3-Dichlorophenacylamino)acrylonitrile

Product 1

HCID 91724Fenpiclonil

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4.2 g of the 3-(2,3-dichlorophenacylamino)acrylonitrile obtained in (a) are reacted in 50 ml of ethanol with 0.5 g of sodium ethylate as described in Example P5(b), affording the title compound in quantitative yield. Melting point: 150°-152° C.

Sources & evidence

ORD record
ord-37f800c6aa9c47ce9efe1766c7d9eae9
Source dataset
uspto-grants-1987_11
Patent number
US04709053

Reaction notes

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