Sodium Hydroxide → HCID 178474552, compound

HRID 24774Notes

Reaction equation

HRID 24774 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[C:24]([N:27]([C:29]1[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=1)[CH3:28])(=[O:26])[CH3:25].[OH-].[Na+]>CN(C=O)C.CO>[C:24]([N:27]([C:29]1[CH:35]=[CH:34][C:32]([NH:33]/[C:13](=[C:6]2\[C:5](=[O:23])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[CH:10][CH:11]=3)/[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:31][CH:30]=1)[CH3:28])(=[O:26])[CH3:25]

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 67068N-(4-Aminophenyl)-N-methylacetamideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

Product 1

HCID 178474552HCID 178474552, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-(N-acetyl-N-methyl-amino)-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-bc4bafadaec842ec8dfda6dea19e8de7
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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