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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24776Generated: October 29, 2026

Sodium Hydroxide → HCID 178485766, compound

https://huagongshe.com/reaction/24776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant4-(N-piperidinomethylcarbonyl-N-methyl-amino)-anilineHCID 22569644—
Reactant1-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinoneHCID 54237888—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 178485766HCID 178485766—

Reaction Steps

Prepared analogously to Example 43 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-(N-piperidinomethylcarbonyl-N-methyl-amino)-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-270be165663e40eba849d19aa046c37a
Source noteuspto-grants-2005_02