Sodium Hydroxide → HCID 178485769, 화합물

HRID 24777노트

반응식

HRID 24777 반응식
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[CH2:24]([N:31]1[CH2:36][CH2:35][N:34]([CH2:37][C:38]([N:40]([C:42]2[CH:48]=[CH:47][C:45]([NH2:46])=[CH:44][CH:43]=2)[CH3:41])=[O:39])[CH2:33][CH2:32]1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1.[OH-].[Na+]>CN(C=O)C.CO>[CH2:24]([N:31]1[CH2:32][CH2:33][N:34]([CH2:37][C:38]([N:40]([C:42]2[CH:43]=[CH:44][C:45]([NH:46]/[C:13](=[C:6]3\[C:5](=[O:23])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[CH:10][CH:11]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:47][CH:48]=2)[CH3:41])=[O:39])[CH2:35][CH2:36]1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

참가 물질

6

반응물 3

HCID 14798Sodium HydroxideHCID 225695334-[N-(4-benzylpiperazinomethylcarbonyl)-N-methylamino]-anilineHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

생성물 1

HCID 178485769HCID 178485769, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 6228Dimethylformamide용매

실험 절차

Prepared analogously to Example 43 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-[N-(4-benzylpiperazinomethylcarbonyl)-N-methylamino]-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

출처 및 근거

ORD 기록
ord-3e12fbf57bf84322ba5aa6308801d045
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

반응 노트

불러오는 중…