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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 247770Generated: October 25, 2026

Methyl Bromide → 1-Methyl-3-(2-amino-thiazol-4-yl)pyridinium bromide

https://huagongshe.com/reaction/247770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl BromideHCID 6323—
Reactant4-(3-Pyridinyl)-2-thiazolamineHCID 154893—
SolventAcetonitrileHCID 6342—
Product1-Methyl-3-(2-amino-thiazol-4-yl)pyridinium bromideHCID 14510179—

Reaction Conditions

Temperature90 °C

Reaction Steps

A suspension of 3-(2-amino-thiazol-4-yl)pyridine (12.84 g) in acetonitrile (450 ml) containing bromomethane (6.84 g) was heated in stirring autoclave at 90° C. for 20 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE034242
Source datasetuspto-grants-1993_05
ORD IDord-6c57e80210b040309ed1fe60593baed2
Source noteuspto-grants-1993_05