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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24786Generated: October 27, 2026

Sodium Hydroxide → 3-{1-[N-(4-cyanophenyl)-N-methyl-amino]-1-phenyl-methylidene}-2-indolinone

https://huagongshe.com/reaction/24786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant4-(Methylamino)benzonitrileHCID 10964551—
Reactant1-Acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinoneHCID 69743657—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
Product3-{1-[N-(4-cyanophenyl)-N-methyl-amino]-1-phenyl-methylidene}-2-indolinoneHCID 69740390—

Reaction Steps

Prepared analogously to Example 2 from 1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone and 4-methylamino-benzonitrile in THF and subsequent treatment with sodium hydroxide solution in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-13797840b9b6404692a82f9251408b5f
Source noteuspto-grants-2005_02