Hydrazine hydrate (1:1) → HCID 178468816, compound

HRID 247886Notes

Reaction equation

HRID 247886 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12](=O)[CH2:13][C:14](=O)[C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:6]=[CH:7][C:8]=1[OH:9].O.[NH2:23][NH2:24]>>[CH2:18]([O:17][C:15]([C:14]1[NH:24][N:23]=[C:12]([CH:11]=[CH:10][C:5]2[CH:6]=[CH:7][C:8]([OH:9])=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:13]=1)=[O:16])[CH3:19]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 53979821Ethyl 6-(3-methoxy-4-hydroxyphenyl)-2,4-dioxo-5-hexenoate

Product 1

HCID 178468816HCID 178468816, compoundYield 51%

Procedure

According to the procedure of Example 1, ethyl 6-(3-methoxy-4-hydroxyphenyl)-2,4-dioxo-5-hexenoate is reacted with hydrazine hydrate to afford ethyl-3-[β-(3-methoxy-4-hydroxyphenyl)ethenyl]-1H-pyrazole-5-carboxylate in 51% yield, mp=99°-101° C.

Sources & evidence

ORD record
ord-79f60575c1544a2c869d15bb618f5c33
Source dataset
uspto-grants-1993_05
Patent number
US05208251

Reaction notes

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