HCID 178418361, compound → HCID 178507619, compound

HRID 24791Notes

Reaction equation

HRID 24791 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([NH:10]/[C:11](=[C:18]2\[C:19](=[O:27])[NH:20][C:21]3[C:26]\2=[CH:25][CH:24]=[CH:23][CH:22]=3)/[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O.[H][H]>C1COCC1.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([NH:10]/[C:11](=[C:18]2\[C:19](=[O:27])[NH:20][C:21]3[C:26]\2=[CH:25][CH:24]=[CH:23][CH:22]=3)/[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:7]=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 178418361HCID 178418361, compoundHCID 178517086HCID 178517086, compound

Product 1

HCID 178507619HCID 178507619, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

3.5 g (0.01 mol) of (Z)-3-[1-(3-nitrophenylamino)-1-phenyl-methylidene}-2-indolinone are dissolved in 200 ml of THF and after the addition of 0.5 g of palladium/charcoal hydrogenated with hydrogen. Then the catalyst is filtered off and concentrated by evaporation.

Workup

  1. filtrationThen the catalyst is filtered off
  2. concentrationconcentrated by evaporation

Sources & evidence

ORD record
ord-0429ba5ee15146f9a7f956b2dfd9d872
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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