HRID247917

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

结构：CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2ccccn2)C(=O)c2ccccc2OC)cc1

HCID19016434

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2cccc[n+]2C)C(=O)c2ccccc2OC)cc1.[I-]

HCID67878949

未命名化合物

CONDITIONS

反应条件

温度: 105 °C

PROCEDURE

实验过程

A mixture of 0.770 g of product from Example 6 and 4.29 ml methyl iodide is heated in a sealed tube at 105° C. for 15 hours. The cooled reaction is concentrated in vacuo to give 0.960 g of the desired product as a thick yellow oil which solidified on standing.

WORKUP

后处理

customThe cooled reaction
concentrationis concentrated in vacuo

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8162f06ca7e64419b0505c424ce402f8
来源数据集: uspto-grants-1993_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05208247
来源说明: uspto-grants-1993_05

反应 SMILES

[CH3:1][O:2][C:3]1[CH:41]=[CH:40][CH:39]=[CH:38][C:4]=1[C:5]([N:7]([CH2:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][N:33]=1)[C:8](=[O:30])[C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:11][CH:10]=1)=[O:6].[CH3:42][I:43]>>[I-:43].[CH3:1][O:2][C:3]1[CH:41]=[CH:40][CH:39]=[CH:38][C:4]=1[C:5]([N:7]([CH2:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][N+:33]=1[CH3:42])[C:8](=[O:30])[C:9]1[CH:10]=[CH:11][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:13][CH:14]=1)=[O:6]