Benzyl Bromide → 2-[[Acetyl[4-(tetradecyloxy)benzoyl]amino]methyl]-1-(phenylmethyl)pyridinium bromide

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Reaction Steps

A mixture of 0.75 g of product from Example 5, 0.412 g of benzyl bromide and 3 ml of acetonitrile is stirred at room temperature for 17.5 hours then heated, in a sealed tube, at 100° C. for 21.25 hours. The cooled reaction mixture is concentrated in vacuo and the residue purified by column chromatography (silica gel: 10% methyl alcohol/chloroform) to give 0.515 g of the desired product.

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