HuagongsheHuagongshe Chemistry Print Report · For research reference only
Myristyl bromide → HCID 53824641, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 3-chloro-4-hydroxybenzoate | HCID 77580 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 53824641 | HCID 53824641 | 96% |
Reaction Steps
A mixture of 100.0 g of 3-chloro-4-(hydroxy)benzoic acid methyl ester, 148.6 g of 1-bromotetradecane, 170.4 g of potassium carbonate and 1 L of acetone is heated at reflux temperature for 40.5 hours. The cooled reaction is filtered, concentrated in vacuo and purified by column chromatography (silica gel:0-2% ethyl acetate/hexane) to give 197.1 g of the desired product as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05208247 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-8b6273f2848f4ae08442ccd08bcd2c7e |
| Source note | uspto-grants-1993_05 |