Potassium Iodide → HCID 54425506, compound

HRID 247955Notes

Reaction equation

HRID 247955 reaction equation
[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[C:6]([O:11][CH3:12])[CH:5]=1.C(=O)([O-])[O-].[K+].[K+].[I-].[K+].[CH3:22][C:23](=O)[CH2:24][CH3:25]>>[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:22][CH2:23][CH2:24][CH2:25][CH2:22][CH2:23][CH2:24][CH2:25][CH2:8][CH2:9][CH2:4][CH2:5][CH2:6][CH3:7])=[C:6]([O:11][CH3:12])[CH:5]=1

Participants

5

Reactant 4

HCID 4875Potassium IodideHCID 6569Methyl Ethyl KetoneHCID 11430Potassium CarbonateHCID 19844Methyl Vanillate

Product 1

HCID 54425506HCID 54425506, compound

Procedure

A mixture of 28.5 g 3-methoxy-4-(hydroxy)benzoic acid methyl ester, 25.94 g of finely powdered potassium carbonate, 0.070 g potassium iodide and 285 ml of 2-butanone is heated at reflux temperature for 41 hours. The reaction is cooled and filtered. The filtrate is concentrated in vacuo and recrystallized from hexane to give 40.8 g of the desired product as white crystals.

Workup

  1. temperatureis heated
  2. temperatureat reflux temperature for 41 hours
  3. temperatureThe reaction is cooled
  4. filtrationfiltered
  5. concentrationThe filtrate is concentrated in vacuo
  6. customrecrystallized from hexane

Sources & evidence

ORD record
ord-1b2a8268a7074a4cba94bdc2b050eabc
Source dataset
uspto-grants-1993_05
Patent number
US05208247

Reaction notes

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